Science Seminar Series: Molecular regulation of stem cell behavior during tissue repair and cancer formation

Tuesday, March 7, 2017 at 11:00 am to 12:00 pm

Classroom Building, Room 170
981 Kensington Way, Stockton, CA

Nestor J. Oviedo, PhD, associate professor in the Department of Molecular & Cell Biology at UC Merced, will be the speaker for the next Science Seminar. 

Oviedo will be presenting his work on identifying the mechanisms of adult stem cell fate determination based on their topographical location in the adult body. Understanding stem cell fate determination is crucial because tissue repair and neoplastic growth are greater in anterior than in posterior regions of adult animals. Despite its critical implications for stem cell biology, carcinogenesis and regenerative medicine, this physiological phenomenon has remained overlooked. Recent findings from his group provide intriguing evidence implying DNA repair mechanisms and cellular signaling through post-translational modifications regulate stem cell fate decision depending on their topographical location in the adult body. We have identified organ-specific cues and evolutionarily conserved cellular signaling pathways that can be therapeutically exploited to control stem cell behavior and cellular transformation in the complexity of the adult body. 

About the Science Seminar Series:
The Science Seminar Series exposes members of the Pacific community to cutting-edge research and development in the biological, biomedical and pharmaceutical sciences and promotes interaction between science departments across the university to foster cross-disciplinary collaborative work within Pacific and with other institutions. The series introduces students, faculty and other interested members to research in diverse bioscience disciplines by the scientific experts themselves with an opportunity to network with speakers during informal campus lunches following the presentations.

The series is sponsored by the Thomas J. Long School of Pharmacy and Health Sciences Department of Physiology and Pharmacology, the College of the Pacific departments of Biological Sciences and Chemistry, the School of Engineering and Computer Science Bioengineering Department and the Office of the Provost.

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